If you're on the hunt for the perfect serum and moisturizer duo that delivers visible results, the buzzworthy combo of Dr. Althea 345 Cream and Anua Niacinamide 10% + Tranexamic Acid Serum might just be your holy grail. Loved by skincare enthusiasts across TikTok and Instagram, this pair is celebrated for its ability to brighten, soothe, and deeply hydrate – all while being gentle enough for daily use across skin types.

© Dr.Althea

Dr. Althea 345 Cream is a lightweight yet intensely moisturizing cream packed with skin-loving ingredients like Ceramides, Panthenol, and Centella Asiatica. These ingredients work together to strengthen the skin barrier, reduce inflammation, and provide lasting hydration. The "345" in its name refers to its simple, clean formulation – 3 types of hyaluronic acid, 4 types of calming plant extracts, and 5 types of skin-repairing ingredients. It's a go-to for those with dry, sensitive, or irritated skin looking for a calm, nourishing finish.

© Anua

Anua Niacinamide 10% + Tranexamic Acid Serum, on the other hand, targets dullness and uneven skin tone. With Niacinamide (Vitamin B3) at its core, this serum improves skin texture, reduces excess oil, and fades dark spots over time. The addition of Tranexamic Acid offers a powerful brightening boost, helping to reduce pigmentation and even out complexion. Plus, it's formulated with hydrating and soothing agents to keep your skin barrier happy and healthy.

© Tiktok

The reason this combo has gone viral on TikTok and Instagram recently? Real users are seeing real results – and fast. The cream locks in moisture and calms the skin, while the serum goes to work on brightening and refining texture. Together, they offer a "balanced diet" for your skin, feeding it a cocktail of Niacinamide, Tranexamic Acid, Hyaluronic Acid, Ceramides, Panthenol, and Centella – a powerhouse mix for radiant, smooth skin.

What makes this the best combo these days is the synergy between the ingredients. While Niacinamide and Tranexamic Acid brighten and even out skin tone, Ceramides and Centella restore and protect the skin barrier. Panthenol and Hyaluronic Acid add intense hydration without clogging pores. Whether your skin is normal, dry, oily, or combination, this duo delivers a glow-up that's both visible and healthy – no wonder everyone’s calling it skincare’s new power couple.

© Tiktok @bloomandbeauty.lk

This powerful combination is especially effective for tackling a variety of common skin concerns, making it a favorite among those dealing with redness and post-acne marks. The Niacinamide and Tranexamic Acid in the serum help fade dark spots and discoloration left behind by breakouts, while the calming and restorative properties of Centella and Panthenol in the cream soothe redness and prevent further irritation. If your skin feels rough, lacks glow, or looks tired from environmental stress or past acne, this duo works overtime to restore clarity, smoothness, and hydration – leaving your skin looking healthier and more balanced over time.

And if this is your first time hearing about these brands, it’s time to add them to your skincare radar. Dr. Althea is a Korean skincare brand loved for its minimal, calming formulas that focus on repairing and protecting the skin barrier – especially great for sensitive or irritated skin. Meanwhile, Anua has been making waves with its gentle but high-performance skincare, especially among those with acne-prone or sensitive skin. Both brands are cruelty-free, ingredient-conscious, and focused on maintaining healthy skin from the inside out.

© Dr.Althea

But how do I use Dr. Althea 345 Cream and Anua Niacinamide 10% + Serum combo effectively?

To use this powerful combo effectively:

 •  Start with a clean, toned face

 •  Apply a few drops of the Anua serum first – gently pat it in until fully absorbed. This allows the Niacinamide and Tranexamic Acid to penetrate the skin and start targeting dark spots, dullness, and uneven tone.

 •  Follow up with the Dr. Althea 345 Cream to seal in hydration and calm the skin. Its ceramides and hyaluronic acid help lock in moisture and reinforce your skin’s natural barrier.

 •  You can use this combo both in the morning and evening

 •  Don’t forget to apply sunscreen during the day to protect your skin and boost the brightening effects.